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Human T-Cell Lymphotropic Virus Type 1-Associated Myelopathy, Sjogren Syndrome, and Lymphocytic Pneumonitis Arch Neurol 53:940-942, Kompoliti,A.,et al, 1996 See this aricle in Pubmed Article Abstract A 40-year-old Creole woman from New Orleans,La,presented with progressive spastic paraparesis and exertional dyspnea.Review of systems revealed chronic complaints consistent with sicca syndrome.She was found to have HTLV-1 associated myelopathy by polymerase chain reaction in the cerebrospinal fluid.Increased levels of SSA,positive results on a Schirmer test,and the findings of biopsy of the minor salivary gland were consistent with Sjogren syndrome.A lung biopsy specimen showed marked lymphocytic infiltration.The present case raises questions about the role of HTLV-1 in the development of autoimmunity.It also happens to be a unique occurrence in a nonendemic area.

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(click to filter results - removes previous filter) human T-lymphotropic virus type I(HTLV-I) lymphocytic pneumonitis myelopathy myelopathy,chronic progressive paraparesis,spastic paraparesis,spastic,tropical polymerase chain reaction sicca syndrome Sjogren's syndrome

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